State Farm Stadium will play host to Monday's Round 5 NFL game between San Francisco 49ers and Arizona Cardinals. The game kicks off at 7:26 am with Arizona Cardinals heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the San Francisco 49ers vs. Arizona Cardinals game and give you our free tips and bets.
When: Monday October 11, 2021 at 7:26 am
Where: State Farm Stadium
Bet: Bet On This Match HERE
San Francisco 49ers vs Arizona Cardinals Odds
San Francisco 49ers vs Arizona Cardinals Preview
There’s still plenty of football left to be played, but this is shaping up to be a critical game for the 49ers in wild and dangerous NFC West.
San Francisco is in the midst of a two-game skid after falling to the Seahawks last week, but that comes as no surprise as Kyle Shanahan’s team continues to battle through injury.
Much like last year, Jimmy Garoppolo is back on the injury report with a calf injury, while the running back spot has been decimated to leave Trey Sermon as the likely starter this week.
None of that bodes particularly well against the undefeated Cardinals, a team that currently leads the league in points scored with an average of 35 a game.
It has to be said that the 49er defence has held the Cardinals to under 26 points in each of their last five meetings, but it just feels like this is a different Arizona team to the ones we’ve seen in the past.
Rookie Trey Lance showed last week that he’s capable of leading San Francisco on scoring drives, but the Cardinals’ defence presents a much tougher test than Seattle’s weak secondary.
All that said, -5.5 feels like a lot for a divisional game, so I feel better about taking Arizona 1-13.
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